Primary Responsibilities
· Targets evaluation, target indications and competitive landscape assessment for RNA-based therapeutics, including siRNA, ASO and related disciplines
· Perform preclinical candidate screening and optimization via combined in vitro and in vivo assays, working withina cross-disciplinary group, including discovery chemistry, CMC and other relevant functions
· Determine mechanism of action of drug targets; design and execute proof-of-concept studies to validate targets together with internal and/or external partners
· Lead projects from inception to development candidate nomination
· Prepare key preclinical, clinical and regulatory documents, and patent application
· Effectively manage multiple programs and deliver quality result within sensitive timelines
· Comply with appropriate SOPs; if needed, train associates to meet requirements; present research findings to project teams, governance bodies, or external meetings
· Effectively communicate across all organizational levels
Qualifications
· PhD in biology, pharmacology, or related discipline with 4+ years of experience in pharmaceutical/biotech industry or academic settings. The level of position will be determined by previous experience and achievements.
· Experience in ASO/siRNA and/or gene/base editing is highly desired.
· Extensive experience conducting preclinical POC studies in the context of liver, extrahepatic tissues, such as nervous system (CNS or PNS), muscle
· Track record of independent research and creativity, as demonstrated by quality publications and/or patents
· Knowledge and ability to develop biochemical and molecular biology assays for RNA and protein quantification
· CRO and remote management of global resources, ranging from costing, execution, and interpretation of results in a timely manner
· Ability to work independently and collaboratively
· Outstanding organizational and time management skills and must be a self-starter with the ability to thrive in a multi-disciplinary, collaborative, fast-paced, and team-oriented environment.
· Excellent verbal and written communication skills
...System Administrator Onsite at Richmond, VA (Locals Only) Job Description: Establishes and implements enterprise level policy and procedure for conducting and maintaining the IT Asset Inventory. Plans and implements both current and future system processes,...
&##128226; We're Hiring! Now Online Job!!! We are actively seeking motivated individuals remote workers for part-time and full-time roles. Earn a daily salary Get paid every day!&##128313;What Youll Do: Basic English required Good environment...
...Job Description LOCATION: PRESHO, SD General carpentry and construction duties, will be assisting general carpenter. To include... ...card/work vehicle possible after 90 days. Pay starts for entry level no experience, 18-20 hourly and more if experienced Will discuss...
...referring physicians, therapists, support staff, University of Florida College of Public Health and Health Professions and the University of... ...clubs, staff mentoring and the ability to be involved with student clinical education and our UF Health accredited residency...
...at least two years' experience working exclusively as a professional in major home appliance repair then you could have what it takes to be an Ortega's Appliance Service Expert Technician! We offer the best benefits available with any appliance repair company in the...