Scientist/Senior Scientist/Principla Scientist, RNA therapeutics Job at Vivatides Therapeutics Inc., Woburn, MA

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  • Vivatides Therapeutics Inc.
  • Woburn, MA

Job Description

Primary Responsibilities

· Targets evaluation, target indications and competitive landscape assessment for RNA-based therapeutics, including siRNA, ASO and related disciplines

· Perform preclinical candidate screening and optimization via combined in vitro and in vivo assays, working withina cross-disciplinary group, including discovery chemistry, CMC and other relevant functions

· Determine mechanism of action of drug targets; design and execute proof-of-concept studies to validate targets together with internal and/or external partners

· Lead projects from inception to development candidate nomination

· Prepare key preclinical, clinical and regulatory documents, and patent application

· Effectively manage multiple programs and deliver quality result within sensitive timelines

· Comply with appropriate SOPs; if needed, train associates to meet requirements; present research findings to project teams, governance bodies, or external meetings

· Effectively communicate across all organizational levels

Qualifications

· PhD in biology, pharmacology, or related discipline with 4+ years of experience in pharmaceutical/biotech industry or academic settings. The level of position will be determined by previous experience and achievements. 

· Experience in ASO/siRNA and/or gene/base editing is highly desired.

· Extensive experience conducting preclinical POC studies in the context of liver, extrahepatic tissues, such as nervous system (CNS or PNS), muscle

· Track record of independent research and creativity, as demonstrated by quality publications and/or patents

· Knowledge and ability to develop biochemical and molecular biology assays for RNA and protein quantification 

· CRO and remote management of global resources, ranging from costing, execution, and interpretation of results in a timely manner

· Ability to work independently and collaboratively 

· Outstanding organizational and time management skills and must be a self-starter with the ability to thrive in a multi-disciplinary, collaborative, fast-paced, and team-oriented environment.

· Excellent verbal and written communication skills

Job Tags

Remote job,

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